STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDL3Rhomboid-related protein 3; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (369 aa)    
Predicted Functional Partners:
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.783
WDR90
WD repeat domain 90.
   
 0.684
MAGI3
Membrane associated guanylate kinase, WW and PDZ domain containing 3.
  
 0.607
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
  
 0.579
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
      
 0.550
NPHS2
NPHS2 stomatin family member, podocin.
   
 0.540
PHB2
Prohibitin.
   
 0.516
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
   
 0.476
LONP2
Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-.
     
 0.472
G1KUA1_ANOCA
NDK domain-containing protein; Belongs to the NDK family.
   
 
 0.456
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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