STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDRKinase insert domain receptor. (1357 aa)    
Predicted Functional Partners:
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.900
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 0.887
VEGFD
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
    
 0.795
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
   
 
 0.746
PDGFB
Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
   
 0.722
GRB2
Growth factor receptor bound protein 2.
   
 0.711
cd34
Uncharacterized protein.
   
  
 0.646
NRP2
Neuropilin; Belongs to the neuropilin family.
     
 0.630
PGF
Placental growth factor; Belongs to the PDGF/VEGF growth factor family.
    
 0.624
PDGFRB
Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
  
0.606
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.