STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100556560Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (481 aa)    
Predicted Functional Partners:
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.995
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.970
TGFB3
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.970
TGFBR1
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
0.969
SMAD2
Mothers against decapentaplegic homolog.
   
 0.960
SMURF2
E3 ubiquitin-protein ligase.
    
 0.951
SMURF1
E3 ubiquitin-protein ligase.
    
 0.951
RHOA
Ras homolog family member A.
   
 0.936
acvrl1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
  
0.921
PPP2R1A
Protein phosphatase 2 scaffold subunit Aalpha.
    
 0.913
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.