STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAD4Mothers against decapentaplegic homolog. (552 aa)    
Predicted Functional Partners:
SMAD1
Mothers against decapentaplegic homolog.
   
0.998
SMAD2
Mothers against decapentaplegic homolog.
   
0.996
smad9
Mothers against decapentaplegic homolog.
   
0.992
SMAD5
Mothers against decapentaplegic homolog.
   
0.992
SMAD3
Mothers against decapentaplegic homolog.
   
0.985
LEF1
Lymphoid enhancer binding factor 1.
    
 0.970
E2F5
E2F transcription factor 5.
    
 0.968
E2F4
E2F transcription factor 4.
    
 0.968
RBL1
RB transcriptional corepressor like 1.
    
 0.957
TFDP1
Transcription factor.
     
 0.956
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.