STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEAK1Pseudopodium enriched atypical kinase 1. (1770 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
     
 0.706
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
      
 0.680
RND2
Rho family GTPase 2.
     
 0.601
RHOV
Ras homolog family member V.
    
 0.563
IP6K1
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.549
TRRAP
Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.
      
 0.526
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
      
 0.491
RCN2
Reticulocalbin 2.
      
 0.481
FAM20B
FAM20B glycosaminoglycan xylosylkinase.
      
 0.471
ITSN1
Intersectin 1.
     
 0.454
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.