STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (920 aa)    
Predicted Functional Partners:
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
  
0.990
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
  
0.951
GRIA3
Glutamate ionotropic receptor AMPA type subunit 3.
  
 
0.908
GRIP1
Glutamate receptor interacting protein 1.
   
 0.796
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
   
0.786
PICK1
Protein interacting with PRKCA 1.
    
 0.786
CACNG8
Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
    
 0.772
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
   
0.769
GRIN1
Glutamate ionotropic receptor NMDA type subunit 1.
   
0.757
CACNG4
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 0.754
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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