STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN13Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2466 aa)    
Predicted Functional Partners:
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 
 0.776
rapgef6
Uncharacterized protein.
    
 0.698
GAB1
GRB2 associated binding protein 1.
    
 0.669
FAS
Fas cell surface death receptor.
   
 
 0.664
LOC100554461
Uncharacterized protein.
    
 0.605
LOC103282413
Uncharacterized protein.
    
 0.605
RND2
Rho family GTPase 2.
    
  0.572
PLEKHA1
Pleckstrin homology domain containing A1.
    
  0.564
ARHGAP29
Rho GTPase activating protein 29.
    
 
 0.521
CNTN1
Contactin 1.
    
 0.519
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.