STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tox3HMG box domain-containing protein. (333 aa)    
Predicted Functional Partners:
PTPRD
Protein tyrosine phosphatase receptor type D.
   
 
 0.721
ACTR8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.608
LOC103282303
Uncharacterized protein.
    
 0.602
HCRTR2
Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.583
GTF2H1
General transcription factor IIH subunit 1.
    
 0.580
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 0.568
ACTR5
Actin related protein 5; Belongs to the actin family.
    
 0.565
GTF2H3
General transcription factor IIH subunit 3.
    
 0.565
LOC100558064
General transcription factor IIH subunit.
   
 0.556
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.550
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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