STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG7Chromosome 12 open reading frame 74. (378 aa)    
Predicted Functional Partners:
TRADD
TNFRSF1A associated via death domain.
    
 0.771
WDFY3
WD repeat and FYVE domain containing 3.
    
 0.634
OPTN
Optineurin.
    
 0.581
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.581
MADD
MAP kinase activating death domain.
    
 0.575
TNFSF15
TNF superfamily member 15.
    
 0.563
LOC100561101
TNF_2 domain-containing protein.
    
 0.563
LOC103278072
TNF_2 domain-containing protein.
    
 0.563
BIRC6
Baculoviral IAP repeat containing 6.
    
 0.548
BAG3
BCL2 associated athanogene 3.
    
 0.535
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.