STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCAF7DDB1 and CUL4 associated factor 7. (342 aa)    
Predicted Functional Partners:
DYRK1A
Dual specificity tyrosine phosphorylation regulated kinase 1A.
   
 
 0.959
DDB1
Damage specific DNA binding protein 1.
    
 0.941
DYRK1B
Dual specificity tyrosine phosphorylation regulated kinase 1B.
   
 
 0.885
DTL
Denticleless E3 ubiquitin protein ligase homolog.
     
 0.870
CUL4A
Cullin 4A; Belongs to the cullin family.
    
 0.853
CUL4B
Cullin 4B; Belongs to the cullin family.
    
 0.853
dcaf11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.823
HIPK2
Homeodomain interacting protein kinase 2.
   
 
 0.819
WDTC1
WD and tetratricopeptide repeats 1.
   
 
  0.796
RBX1
Ring-box 1.
     
 0.794
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.