STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1KProtein phosphatase, Mg2+/Mn2+ dependent 1K. (371 aa)    
Predicted Functional Partners:
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
   
 0.862
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.805
bckdha
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.778
AANAT
Aralkylamine N-acetyltransferase.
    
   0.694
DLD
Dihydrolipoyl dehydrogenase.
   
 0.533
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
     
 0.489
PPTC7
Protein phosphatase; Belongs to the PP2C family.
    
 
 0.452
BCKDK
Protein-serine/threonine kinase.
   
 
 0.446
MTFMT
Mitochondrial methionyl-tRNA formyltransferase.
  
   0.442
VAPA
VAMP associated protein A.
    
  0.431
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.