STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK3Non-specific serine/threonine protein kinase. (557 aa)    
Predicted Functional Partners:
CDC42
Uncharacterized protein.
   
 0.983
NCK2
Cytoplasmic protein.
    
 0.971
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.969
LIMK1
LIM domain kinase 1.
    
0.959
ITSN2
Intersectin 2.
    
 0.959
RAC3
Rac family small GTPase 3.
   
 0.957
RAC1
Rac family small GTPase 1.
   
 0.957
RAC2
Rac family small GTPase 2.
   
 0.957
MYO6
Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
  0.937
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 
0.929
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.