STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)    
Predicted Functional Partners:
CCND1
Cyclin D1.
   
 0.996
CCND3
Cyclin D3; Belongs to the cyclin family.
   
 0.991
RB1
RB transcriptional corepressor 1.
   
 0.988
CDKN2C
Cyclin dependent kinase inhibitor 2C.
   
 0.988
LOC100562668
ANK_REP_REGION domain-containing protein.
    
 0.985
RBL1
RB transcriptional corepressor like 1.
   
 0.965
RBL2
RB transcriptional corepressor like 2.
   
 0.965
CDKN1B
Cyclin dependent kinase inhibitor 1B.
   
 0.964
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 0.964
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.960
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.