STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSDMEGasdermin E. (507 aa)    
Predicted Functional Partners:
LOC100554079
CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.
     
 0.674
OSBPL6
Oxysterol-binding protein; Belongs to the OSBP family.
 
    
 0.674
CASP2
Caspase 2; Belongs to the peptidase C14A family.
     
 0.659
hnrnpa3
Uncharacterized protein.
      
 0.659
Nfe2l3
BZIP domain-containing protein.
      
 0.659
HNRNPA2B1
Heterogeneous nuclear ribonucleoprotein A2/B1.
      
 0.654
CASP9
Caspase 9; Belongs to the peptidase C14A family.
  
  
 0.641
LOC100552932
CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.
     
 0.637
CASP6
Caspase 6; Belongs to the peptidase C14A family.
     
 0.587
MLKL
Mixed lineage kinase domain like pseudokinase.
      
 0.581
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.