STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F9Coagulation factor IX. (402 aa)    
Predicted Functional Partners:
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
0.782
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
   
 0.712
F5
Coagulation factor V.
   
 0.674
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
   
 0.642
EGLN3
Egl-9 family hypoxia inducible factor 3.
    
 
 0.593
SERPINA10
Serpin family A member 10; Belongs to the serpin family.
   
 0.581
F3
Coagulation factor III, tissue factor.
    
 0.563
MST1R
Macrophage stimulating 1 receptor.
    
  0.560
MET
MET proto-oncogene, receptor tyrosine kinase.
    
  0.560
PROC
Protein C, inactivator of coagulation factors Va and VIIIa.
  
 
0.530
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (20%) [HD]