STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (994 aa)    
Predicted Functional Partners:
ARID4B
AT-rich interaction domain 4B.
    
 0.827
ARID4A
AT-rich interaction domain 4A.
    
 0.827
KAT6A
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.707
KAT2A
Lysine acetyltransferase 2A.
   
 0.688
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.650
rbbp4
RB binding protein 4, chromatin remodeling factor.
   
 0.605
WDR73
WD repeat domain 73.
   
 0.605
hdac8
Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
  
 
0.577
RANBP2
RAN binding protein 2.
   
 0.574
SIN3B
SIN3 transcription regulator family member B.
   
 0.567
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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