STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pik3r3Uncharacterized protein. (473 aa)    
Predicted Functional Partners:
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.979
PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.978
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.971
LOC100567364
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.971
IRS1
Insulin receptor substrate 1.
    
 0.967
IRS4
Insulin receptor substrate 4.
    
 0.967
GAB1
GRB2 associated binding protein 1.
    
 0.966
PDPK1
3-phosphoinositide dependent protein kinase 1.
     
 0.957
ITSN2
Intersectin 2.
    
 0.956
ERBB2
Receptor protein-tyrosine kinase.
    
 0.946
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.