STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEK2NIMA related kinase 2. (446 aa)    
Predicted Functional Partners:
bub1b
BUB1 N-terminal domain-containing protein.
   
 0.997
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.996
CDC27
Cell division cycle 27.
    
 0.996
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 0.988
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.979
ANAPC1
Anaphase promoting complex subunit 1.
    
 0.961
CDC20
Cell division cycle 20.
   
 0.960
CDC20B
Cell division cycle 20B.
   
 0.960
CDC23
Cell division cycle 23.
    
 0.954
CDC26
Cell division cycle 26.
    
 0.953
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.