STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCOA3Nuclear receptor coactivator. (1398 aa)    
Predicted Functional Partners:
RXRA
Retinoid X receptor alpha.
   
 0.901
ar
Androgen receptor.
    
 0.838
esr1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily.
    
 0.837
VDR
Vitamin D receptor.
    
 0.812
CREBBP
CREB binding protein.
   
 0.786
NR3C1
Nuclear receptor subfamily 3 group C member 1.
   
 0.784
NR1H4
Nuclear receptor subfamily 1 group H member 4.
    
 0.763
NR1H3
Nuclear receptor subfamily 1 group H member 3.
    
 0.762
NR1H2
Nuclear receptor subfamily 1 group H member 2.
    
 0.762
PPARA
Peroxisome proliferator activated receptor alpha.
    
 0.752
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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