STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPN1Calpain 1; Belongs to the peptidase C2 family. (714 aa)    
Predicted Functional Partners:
Bid
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
  0.904
CAPN11
Calpain 11; Belongs to the peptidase C2 family.
  
  
 
0.901
CAPN2
Calpain 2; Belongs to the peptidase C2 family.
  
  
 
0.901
BAK1
BCL2 antagonist/killer 1.
   
 
 0.901
BAX
BCL2 associated X, apoptosis regulator.
     
 0.901
CAST
Calpastatin.
   
 0.718
CAPNS1
Calpain small subunit 1.
   
0.661
ITSN2
Intersectin 2.
   
 
  0.568
tmem110
Uncharacterized protein.
   
 
 0.497
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
   
 
 0.478
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.