STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFNStratifin; Belongs to the 14-3-3 family. (246 aa)    
Predicted Functional Partners:
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.943
CCNB1
Cyclin B1; Belongs to the cyclin family.
    
 0.938
ccnb3
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
    
 0.932
LOC103282543
Uncharacterized protein.
   
 0.807
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.731
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.
  
0.707
MDM2
MDM2 proto-oncogene.
    
 0.687
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.685
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.685
FOXO1
Forkhead box O1.
    
 0.683
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.