STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLK4CDC like kinase 4; Belongs to the protein kinase superfamily. (477 aa)    
Predicted Functional Partners:
IRX1
Iroquois homeobox 1.
   
  
 0.521
HEY1
Hes related family bHLH transcription factor with YRPW motif 1.
      
 0.445
relb
RELB proto-oncogene, NF-kB subunit.
    
 
 0.434
CACNB3
Calcium voltage-gated channel auxiliary subunit beta 3.
   
  
 0.430
PCGF1
Polycomb group ring finger 1.
    
 
 0.427
CIRBP
Cold inducible RNA binding protein.
    
 
 0.427
C2CD2
C2 calcium dependent domain containing 2.
      
 0.422
PCGF6
Polycomb group ring finger 6.
    
 
 0.422
S100Z
Protein S100; Belongs to the S-100 family.
    
 
 0.421
ATP2B1
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
 
 0.420
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.