STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (755 aa)    
Predicted Functional Partners:
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
    
 0.957
PIK3R5
Phosphoinositide-3-kinase regulatory subunit 5.
   
 
0.917
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
     
 0.912
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
     
 0.912
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
     
 0.912
gnai2
Uncharacterized protein.
     
  0.900
GNAI3
G protein subunit alpha i3.
     
  0.900
GNAI1
G protein subunit alpha i1.
     
  0.900
PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.686
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.686
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.