STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBKSRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (310 aa)    
Predicted Functional Partners:
RPIA
Ribose 5-phosphate isomerase A.
    
 0.958
TKT
Transketolase.
  
 0.955
PRPS2
Phosphoribosyl pyrophosphate synthetase 2.
  
 0.945
prps1
Uncharacterized protein.
  
 0.945
PGM2
Phosphoglucomutase 2; Belongs to the phosphohexose mutase family.
  
 
 0.943
DERA
Deoxyribose-phosphate aldolase.
    
 0.942
PGM1
Phosphoglucomutase 1; Belongs to the phosphohexose mutase family.
   
 0.930
GPI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.841
UPP2
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
   
 0.819
LOC100556121
PfkB domain-containing protein.
  
 
 0.798
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.