STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RXRBRetinoid X receptor beta. (254 aa)    
Predicted Functional Partners:
RXRA
Retinoid X receptor alpha.
  
  
 
0.901
LOC100554391
NR LBD domain-containing protein.
 
      0.807
PPARA
Peroxisome proliferator activated receptor alpha.
     
 
0.800
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
     
 
0.800
PPARD
Peroxisome proliferator activated receptor delta.
     
 
0.800
TCF19
Transcription factor 19.
      
 0.760
ASRGL1
Asparaginase and isoaspartyl peptidase 1.
   
  
 0.661
VPS52
VPS52 subunit of GARP complex.
    
 
 0.657
procr
MHC_I-like_Ag-recog domain-containing protein.
      
 0.654
RPS18
Ribosomal protein S18; Belongs to the universal ribosomal protein uS13 family.
    
 
 0.432
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.