STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nbaC3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (177 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
  
  0.989
SEA28667.1
Aminocarboxymuconate-semialdehyde decarboxylase.
 
  
  0.967
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
 
     0.834
SEA28608.1
3-oxoacyl-[acyl-carrier protein] reductase.
 
  
  0.681
SEA14344.1
Tryptophan 2,3-dioxygenase apoenzyme.
  
  
  0.645
SDZ91170.1
ABC-type nitrate/sulfonate/bicarbonate transport system, substrate-binding protein.
  
     0.624
SEA28693.1
Predicted O-methyltransferase YrrM.
       0.553
SEA67332.1
Kynurenine formamidase.
 
     0.515
SEA28548.1
2-aminomuconate deaminase.
 
    0.511
SEA28578.1
Aminomuconate-semialdehyde/2-hydroxymuconate-6- semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
     0.442
Your Current Organism:
Bizionia paragorgiae
NCBI taxonomy Id: 283786
Other names: B. paragorgiae, Bizionia paragorgiae Nedashkovskaya et al. 2005, DSM 23842, KCTC 12304, KMM 6029, LMG 22571, LMG:22571
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