R7TGR9_CAPTE protein (Capitella teleta) - STRING interaction network

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Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Score

R7TGR9_CAPTE

ANK_REP_REGION domain-containing protein. (93 aa)

Predicted Functional Partners:

R7TXY8_CAPTE

0.880

R7VI43_CAPTE

0.861

R7THY5_CAPTE

0.839

R7ULX5_CAPTE

0.839

R7UT37_CAPTE

0.839

R7U0T4_CAPTE

0.833

R7U554_CAPTE

0.757

R7V3D9_CAPTE

0.756

R7TJP2_CAPTE

0.753

R7UI33_CAPTE

0.753

Your Current Organism:

Capitella teleta

NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R7TGR9_CAPTE	R7THY5_CAPTE	R7TGR9	R7THY5	ANK_REP_REGION domain-containing protein.	RGS domain-containing protein.	0.839
R7TGR9_CAPTE	R7TJP2_CAPTE	R7TGR9	R7TJP2	ANK_REP_REGION domain-containing protein.	cGMP-dependent protein kinase.	0.753
R7TGR9_CAPTE	R7TXY8_CAPTE	R7TGR9	R7TXY8	ANK_REP_REGION domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.880
R7TGR9_CAPTE	R7U0T4_CAPTE	R7TGR9	R7U0T4	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.833
R7TGR9_CAPTE	R7U554_CAPTE	R7TGR9	R7U554	ANK_REP_REGION domain-containing protein.	Ubiquitin-like domain-containing protein.	0.757
R7TGR9_CAPTE	R7UI33_CAPTE	R7TGR9	R7UI33	ANK_REP_REGION domain-containing protein.	cGMP-dependent protein kinase.	0.753
R7TGR9_CAPTE	R7ULX5_CAPTE	R7TGR9	R7ULX5	ANK_REP_REGION domain-containing protein.	RGS domain-containing protein.	0.839
R7TGR9_CAPTE	R7UT37_CAPTE	R7TGR9	R7UT37	ANK_REP_REGION domain-containing protein.	PDZ domain-containing protein.	0.839
R7TGR9_CAPTE	R7V3D9_CAPTE	R7TGR9	R7V3D9	ANK_REP_REGION domain-containing protein.	Serine/threonine-protein phosphatase.	0.756
R7TGR9_CAPTE	R7VI43_CAPTE	R7TGR9	R7VI43	ANK_REP_REGION domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.861
R7THY5_CAPTE	R7TGR9_CAPTE	R7THY5	R7TGR9	RGS domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.839
R7THY5_CAPTE	R7TJP2_CAPTE	R7THY5	R7TJP2	RGS domain-containing protein.	cGMP-dependent protein kinase.	0.758
R7THY5_CAPTE	R7U554_CAPTE	R7THY5	R7U554	RGS domain-containing protein.	Ubiquitin-like domain-containing protein.	0.773
R7THY5_CAPTE	R7UI33_CAPTE	R7THY5	R7UI33	RGS domain-containing protein.	cGMP-dependent protein kinase.	0.758
R7THY5_CAPTE	R7V3D9_CAPTE	R7THY5	R7V3D9	RGS domain-containing protein.	Serine/threonine-protein phosphatase.	0.413
R7THY5_CAPTE	R7VI43_CAPTE	R7THY5	R7VI43	RGS domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.849
R7TJP2_CAPTE	R7TGR9_CAPTE	R7TJP2	R7TGR9	cGMP-dependent protein kinase.	ANK_REP_REGION domain-containing protein.	0.753
R7TJP2_CAPTE	R7THY5_CAPTE	R7TJP2	R7THY5	cGMP-dependent protein kinase.	RGS domain-containing protein.	0.758
R7TJP2_CAPTE	R7ULX5_CAPTE	R7TJP2	R7ULX5	cGMP-dependent protein kinase.	RGS domain-containing protein.	0.758
R7TJP2_CAPTE	R7UT37_CAPTE	R7TJP2	R7UT37	cGMP-dependent protein kinase.	PDZ domain-containing protein.	0.758

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006383

Transcription by RNA polymerase III

6 of 20

2.48

4.96

1.46e-10

GO:0006384

Transcription initiation from RNA polymerase III promoter

4 of 6

2.83

3.83

7.83e-08

GO:0006351

Transcription, DNA-templated

8 of 185

1.64

2.93

2.04e-09

GO:0006352

DNA-templated transcription, initiation

5 of 54

1.97

2.8

8.23e-07

GO:0070898

RNA polymerase III preinitiation complex assembly

2 of 2

3.0

1.61

0.0012

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140223

General transcription initiation factor activity

3 of 16

2.28

1.61

0.00092

GO:0050464

Nitrate reductase (NADPH) activity

2 of 2

3.0

1.41

0.0028

GO:0000995

RNA polymerase III general transcription initiation factor activity

2 of 2

3.0

1.41

0.0028

GO:0043546

Molybdopterin cofactor binding

2 of 5

2.61

1.31

0.0041

GO:0030151

Molybdenum ion binding

2 of 11

2.26

1.14

0.0077

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0090576

RNA polymerase III transcription regulator complex

5 of 5

3.0

5.49

6.98e-11

GO:0000127

Transcription factor TFIIIC complex

3 of 3

3.0

2.96

4.07e-06

GO:0000126

Transcription factor TFIIIB complex

2 of 2

3.0

1.64

0.0011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:834

Transcription factor TFIIIC complex, and Histidine phosphatase superfamily, clade-1

4 of 5

2.91

3.77

1.14e-07

CL:1661

RNA polymerase III complex, and Transcription factor TFIIIB complex

3 of 20

2.18

1.84

0.00028

CL:13449

Oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor, and Cytochrome b5, heme-binding site

2 of 7

2.46

1.42

0.0024

CL:1481

RNA Polymerase II Pre-transcription Events, and RNA polymerase

4 of 117

1.54

1.41

0.00049

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-76066

RNA Polymerase III Transcription Initiation From Type 2 Promoter

7 of 24

2.47

6.21

1.98e-13

MAP-76061

RNA Polymerase III Transcription Initiation From Type 1 Promoter

7 of 24

2.47

6.21

1.98e-13

MAP-76046

RNA Polymerase III Transcription Initiation

7 of 24

2.47

6.21

1.98e-13

MAP-74158

RNA Polymerase III Transcription

7 of 24

2.47

6.21

1.98e-13

MAP-74160

Gene expression (Transcription)

8 of 540

1.17

1.45

9.18e-07

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03404

Mo-co oxidoreductase dimerisation domain

2 of 4

2.7

1.03

0.0135

PF00174

Oxidoreductase molybdopterin binding domain

2 of 4

2.7

1.03

0.0135

PF00970

Oxidoreductase FAD-binding domain

2 of 7

2.46

1.02

0.0135

PF00175

Oxidoreductase NAD-binding domain

2 of 15

2.13

0.82

0.0304

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036374

Oxidoreductase, molybdopterin-binding domain superfamily

2 of 4

2.7

0.79

0.0374

IPR008335

Eukaryotic molybdopterin oxidoreductase

2 of 4

2.7

0.79

0.0374

IPR005066

Moybdenum cofactor oxidoreductase, dimerisation

2 of 4

2.7

0.79

0.0374

IPR000572

Oxidoreductase, molybdopterin-binding domain

2 of 4

2.7

0.79

0.0374

IPR008333

Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain

2 of 7

2.46

0.78

0.0374

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00384

DNA binding domain with preference for A/T rich regions

2 of 11

2.26

0.9

0.0218

SM01117

Cytochrome b5-like Heme/Steroid binding domain

2 of 24

1.92

0.71

0.0452

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