R7TY14_CAPTE protein (Capitella teleta) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

R7TY14_CAPTE

G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (419 aa)

Predicted Functional Partners:

R7U3M9_CAPTE

0.679

R7TNS1_CAPTE

0.607

R7TPP3_CAPTE

0.599

R7UMT5_CAPTE

0.564

R7T6I2_CAPTE

0.560

R7VKR1_CAPTE

0.558

R7UEA4_CAPTE

0.555

R7UXP1_CAPTE

0.555

R7T3B7_CAPTE

0.543

R7TN34_CAPTE

0.543

Your Current Organism:

Capitella teleta

NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R7T3B7_CAPTE	R7T6I2_CAPTE	R7T3B7	R7T6I2	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.985
R7T3B7_CAPTE	R7TPP3_CAPTE	R7T3B7	R7TPP3	WD_REPEATS_REGION domain-containing protein.	Arrestin_C domain-containing protein.	0.577
R7T3B7_CAPTE	R7TY14_CAPTE	R7T3B7	R7TY14	WD_REPEATS_REGION domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.543
R7T3B7_CAPTE	R7U3M9_CAPTE	R7T3B7	R7U3M9	WD_REPEATS_REGION domain-containing protein.	MAM domain-containing protein.	0.860
R7T3B7_CAPTE	R7UEA4_CAPTE	R7T3B7	R7UEA4	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.950
R7T3B7_CAPTE	R7UMT5_CAPTE	R7T3B7	R7UMT5	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.945
R7T3B7_CAPTE	R7UXP1_CAPTE	R7T3B7	R7UXP1	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.950
R7T3B7_CAPTE	R7VKR1_CAPTE	R7T3B7	R7VKR1	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.962
R7T6I2_CAPTE	R7T3B7_CAPTE	R7T6I2	R7T3B7	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.985
R7T6I2_CAPTE	R7TN34_CAPTE	R7T6I2	R7TN34	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.985
R7T6I2_CAPTE	R7TPP3_CAPTE	R7T6I2	R7TPP3	Uncharacterized protein.	Arrestin_C domain-containing protein.	0.520
R7T6I2_CAPTE	R7TY14_CAPTE	R7T6I2	R7TY14	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.560
R7T6I2_CAPTE	R7U3M9_CAPTE	R7T6I2	R7U3M9	Uncharacterized protein.	MAM domain-containing protein.	0.993
R7T6I2_CAPTE	R7UEA4_CAPTE	R7T6I2	R7UEA4	Uncharacterized protein.	Uncharacterized protein.	0.474
R7T6I2_CAPTE	R7UMT5_CAPTE	R7T6I2	R7UMT5	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.982
R7T6I2_CAPTE	R7VKR1_CAPTE	R7T6I2	R7VKR1	Uncharacterized protein.	Uncharacterized protein.	0.727
R7TN34_CAPTE	R7T6I2_CAPTE	R7TN34	R7T6I2	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.985
R7TN34_CAPTE	R7TPP3_CAPTE	R7TN34	R7TPP3	WD_REPEATS_REGION domain-containing protein.	Arrestin_C domain-containing protein.	0.577
R7TN34_CAPTE	R7TY14_CAPTE	R7TN34	R7TY14	WD_REPEATS_REGION domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.543
R7TN34_CAPTE	R7U3M9_CAPTE	R7TN34	R7U3M9	WD_REPEATS_REGION domain-containing protein.	MAM domain-containing protein.	0.860

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.858

expected number of edges:

10

PPI enrichment p-value:

0.000168

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 107

1.48

2.8

1.37e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 54

1.78

4.42

1.30e-14

GO:0019843

rRNA binding

9 of 45

1.82

4.3

2.70e-13

GO:1901363

Heterocyclic compound binding

10 of 1021

0.51

0.39

0.0038

GO:0097159

Organic cyclic compound binding

10 of 1021

0.51

0.39

0.0038

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 59

1.74

4.32

5.48e-15

GO:0015935

Small ribosomal subunit

4 of 8

2.21

3.1

5.74e-07

GO:0005622

Intracellular anatomical structure

11 of 1443

0.4

0.34

0.00075

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:37185344

(2023) Independent origins and evolution of the secondary replicons of the class Gammaproteobacteria.

4 of 29

1.65

1.34

0.0012

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:125

Ribosome

10 of 32

2.01

5.87

1.30e-16

CL:166

Small ribosomal subunit, and Ribosome

6 of 11

2.25

4.74

8.47e-11

CL:169

Small ribosomal subunit, and rRNA binding

3 of 5

2.29

2.25

4.82e-05

CL:126

Ribosome

4 of 20

1.82

2.12

2.09e-05

CL:127

Ribosome

3 of 12

1.91

1.68

0.00037

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pagc03010

Ribosome

10 of 53

1.79

4.62

1.54e-15

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0015935

Small ribosomal subunit

10 of 20

2.21

7.39

9.16e-19

GOCC:0022627

Cytosolic small ribosomal subunit

9 of 19

2.19

6.58

1.88e-16

GOCC:0005829

Cytosol

10 of 889

0.57

0.48

0.00018

GOCC:0005622

Intracellular

11 of 1433

0.4

0.34

0.00090

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

7 of 51

1.65

2.78

1.40e-08

KW-0687

Ribonucleoprotein

7 of 51

1.65

2.78

1.40e-08

KW-0699

rRNA-binding

5 of 30

1.74

2.36

2.19e-06

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