R7U0N6_CAPTE protein (Capitella teleta) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

R7U0N6_CAPTE

Uncharacterized protein. (224 aa)

Predicted Functional Partners:

R7VCJ3_CAPTE

0.860

R7V4Z9_CAPTE

0.813

R7U0U4_CAPTE

0.805

R7TNG7_CAPTE

0.780

R7T4V5_CAPTE

0.757

R7U171_CAPTE

0.757

R7UGR4_CAPTE

0.750

R7UQ62_CAPTE

0.737

R7UY33_CAPTE

0.737

R7TWY7_CAPTE

0.730

Your Current Organism:

Capitella teleta

NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R7T4V5_CAPTE	R7TWY7_CAPTE	R7T4V5	R7TWY7	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.406
R7T4V5_CAPTE	R7U0N6_CAPTE	R7T4V5	R7U0N6	Uncharacterized protein.	Uncharacterized protein.	0.757
R7T4V5_CAPTE	R7U0U4_CAPTE	R7T4V5	R7U0U4	Uncharacterized protein.	Uncharacterized protein.	0.789
R7TNG7_CAPTE	R7TWY7_CAPTE	R7TNG7	R7TWY7	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.677
R7TNG7_CAPTE	R7U0N6_CAPTE	R7TNG7	R7U0N6	Uncharacterized protein.	Uncharacterized protein.	0.780
R7TNG7_CAPTE	R7U0U4_CAPTE	R7TNG7	R7U0U4	Uncharacterized protein.	Uncharacterized protein.	0.478
R7TWY7_CAPTE	R7T4V5_CAPTE	R7TWY7	R7T4V5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.406
R7TWY7_CAPTE	R7TNG7_CAPTE	R7TWY7	R7TNG7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.677
R7TWY7_CAPTE	R7U0N6_CAPTE	R7TWY7	R7U0N6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.730
R7TWY7_CAPTE	R7U0U4_CAPTE	R7TWY7	R7U0U4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.406
R7TWY7_CAPTE	R7U171_CAPTE	R7TWY7	R7U171	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.406
R7TWY7_CAPTE	R7UGR4_CAPTE	R7TWY7	R7UGR4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.505
R7U0N6_CAPTE	R7T4V5_CAPTE	R7U0N6	R7T4V5	Uncharacterized protein.	Uncharacterized protein.	0.757
R7U0N6_CAPTE	R7TNG7_CAPTE	R7U0N6	R7TNG7	Uncharacterized protein.	Uncharacterized protein.	0.780
R7U0N6_CAPTE	R7TWY7_CAPTE	R7U0N6	R7TWY7	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.730
R7U0N6_CAPTE	R7U0U4_CAPTE	R7U0N6	R7U0U4	Uncharacterized protein.	Uncharacterized protein.	0.805
R7U0N6_CAPTE	R7U171_CAPTE	R7U0N6	R7U171	Uncharacterized protein.	Uncharacterized protein.	0.757
R7U0N6_CAPTE	R7UGR4_CAPTE	R7U0N6	R7UGR4	Uncharacterized protein.	Uncharacterized protein.	0.750
R7U0N6_CAPTE	R7UQ62_CAPTE	R7U0N6	R7UQ62	Uncharacterized protein.	Zmiz1_N domain-containing protein.	0.737
R7U0N6_CAPTE	R7UY33_CAPTE	R7U0N6	R7UY33	Uncharacterized protein.	SP-RING-type domain-containing protein.	0.737

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

33

average node degree:

6

avg. local clustering coefficient:

0.888

expected number of edges:

11

PPI enrichment p-value:

1.06e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032511

Late endosome to vacuole transport via multivesicular body sorting pathway

3 of 13

2.54

1.61

0.0011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:30572

Mixed, incl. Late endosome to vacuole transport via multivesicular body sorting pathway, and HCN channels

9 of 30

2.66

9.23

1.61e-19

CL:30574

Mixed, incl. Late endosome to vacuole transport via multivesicular body sorting pathway, and Polypeptide N-acetylgalactosaminyltransferase activity

8 of 18

2.83

9.07

2.19e-18

CL:30577

Mixed, incl. Synaptonemal complex protein 2-like, and Rab-GTPase-TBC domain

5 of 6

3.1

5.88

1.49e-11

CL:30595

Vps55/LEPROT, and Uncharacterised protein family UPF0220

3 of 5

2.96

2.81

7.42e-06

CL:19564

Dystrophin-associated glycoprotein complex, and EF-hand

2 of 14

2.33

0.87

0.0251

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016012

Sarcoglycan complex

2 of 5

2.78

1.04

0.0129

GOCC:0005927

Muscle tendon junction

2 of 6

2.7

1.04

0.0129

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF05255

Uncharacterised protein family (UPF0220)

2 of 2

3.18

1.3

0.0046

PF04790

Sarcoglycan complex subunit protein

2 of 5

2.78

1.15

0.0081

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007919

Uncharacterised protein family UPF0220

2 of 2

3.18

1.02

0.0145

IPR039972

Sarcoglycan gamma/delta/zeta

2 of 4

2.88

0.97

0.0181

IPR006875

Sarcoglycan complex subunit protein

2 of 5

2.78

0.96

0.0181

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