STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R7USV4_CAPTECytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. (327 aa)    
Predicted Functional Partners:
R7U248_CAPTE
Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
    
 0.901
R7UV44_CAPTE
Uncharacterized protein.
   
  
 0.898
R7TR62_CAPTE
WD_REPEATS_REGION domain-containing protein.
   
    0.894
R7V4G8_CAPTE
Uncharacterized protein.
  
  
 0.873
R7V659_CAPTE
Uncharacterized protein.
   
 
  0.872
R7U7U1_CAPTE
6PF2K domain-containing protein.
      0.840
R7TWE2_CAPTE
Uncharacterized protein.
   
  
 0.816
R7TZP7_CAPTE
Uncharacterized protein.
  
 
 0.772
R7T8Q6_CAPTE
Uncharacterized protein; Belongs to the DEAD box helicase family.
  
  
 0.770
R7U3B4_CAPTE
RNA helicase.
  
  
 0.770
Your Current Organism:
Capitella teleta
NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009
Server load: low (26%) [HD]