R7UWZ3_CAPTE protein (Capitella teleta) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

R7UWZ3_CAPTE

G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family. (895 aa)

Predicted Functional Partners:

R7U3M9_CAPTE

0.815

R7UFK9_CAPTE

0.762

R7UVB1_CAPTE

0.619

R7V1I9_CAPTE

0.619

R7UHF2_CAPTE

0.613

R7TBK6_CAPTE

0.584

R7UHQ5_CAPTE

0.584

R7T472_CAPTE

0.583

R7UCJ2_CAPTE

0.577

R7U0F8_CAPTE

0.571

Your Current Organism:

Capitella teleta

NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R7T472_CAPTE	R7TBK6_CAPTE	R7T472	R7TBK6	Uncharacterized protein; Belongs to the NDK family.	Uncharacterized protein.	0.930
R7T472_CAPTE	R7U3M9_CAPTE	R7T472	R7U3M9	Uncharacterized protein; Belongs to the NDK family.	MAM domain-containing protein.	0.430
R7T472_CAPTE	R7UCJ2_CAPTE	R7T472	R7UCJ2	Uncharacterized protein; Belongs to the NDK family.	Uncharacterized protein.	0.813
R7T472_CAPTE	R7UFK9_CAPTE	R7T472	R7UFK9	Uncharacterized protein; Belongs to the NDK family.	Uncharacterized protein.	0.866
R7T472_CAPTE	R7UHF2_CAPTE	R7T472	R7UHF2	Uncharacterized protein; Belongs to the NDK family.	Uncharacterized protein.	0.400
R7T472_CAPTE	R7UHQ5_CAPTE	R7T472	R7UHQ5	Uncharacterized protein; Belongs to the NDK family.	Uncharacterized protein.	0.601
R7T472_CAPTE	R7UWZ3_CAPTE	R7T472	R7UWZ3	Uncharacterized protein; Belongs to the NDK family.	G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family.	0.583
R7TBK6_CAPTE	R7T472_CAPTE	R7TBK6	R7T472	Uncharacterized protein.	Uncharacterized protein; Belongs to the NDK family.	0.930
R7TBK6_CAPTE	R7UWZ3_CAPTE	R7TBK6	R7UWZ3	Uncharacterized protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family.	0.584
R7U0F8_CAPTE	R7U3M9_CAPTE	R7U0F8	R7U3M9	Protein kinase domain-containing protein.	MAM domain-containing protein.	0.874
R7U0F8_CAPTE	R7UCJ2_CAPTE	R7U0F8	R7UCJ2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.438
R7U0F8_CAPTE	R7UFK9_CAPTE	R7U0F8	R7UFK9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.511
R7U0F8_CAPTE	R7UHF2_CAPTE	R7U0F8	R7UHF2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.741
R7U0F8_CAPTE	R7UVB1_CAPTE	R7U0F8	R7UVB1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.669
R7U0F8_CAPTE	R7UWZ3_CAPTE	R7U0F8	R7UWZ3	Protein kinase domain-containing protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family.	0.571
R7U0F8_CAPTE	R7V1I9_CAPTE	R7U0F8	R7V1I9	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.755
R7U3M9_CAPTE	R7T472_CAPTE	R7U3M9	R7T472	MAM domain-containing protein.	Uncharacterized protein; Belongs to the NDK family.	0.430
R7U3M9_CAPTE	R7U0F8_CAPTE	R7U3M9	R7U0F8	MAM domain-containing protein.	Protein kinase domain-containing protein.	0.874
R7U3M9_CAPTE	R7UFK9_CAPTE	R7U3M9	R7UFK9	MAM domain-containing protein.	Uncharacterized protein.	0.535
R7U3M9_CAPTE	R7UVB1_CAPTE	R7U3M9	R7UVB1	MAM domain-containing protein.	Uncharacterized protein.	0.429

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Network Stats

number of nodes:

10

number of edges:

38

average node degree:

7.6

avg. local clustering coefficient:

0.903

expected number of edges:

10

PPI enrichment p-value:

2.79e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031463

Cul3-RING ubiquitin ligase complex

4 of 40

2.26

2.57

9.83e-06

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:37495603

(2023) A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

3 of 26

2.33

0.87

0.0251

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:27170

Mostly uncharacterized, incl. Cerebellum maturation, and Telomeric loop formation

3 of 18

2.49

1.7

0.00072

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

CFA-8951664

Neddylation

5 of 214

1.63

1.71

0.00010

CFA-983168

Antigen processing: Ubiquitination & Proteasome degradation

4 of 280

1.42

0.95

0.0067

CFA-597592

Post-translational protein modification

6 of 1073

1.01

0.72

0.0067

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031463

Cul3-RING ubiquitin ligase complex

3 of 31

2.25

1.53

0.0013

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0880

Kelch repeat

3 of 48

2.06

1.54

0.0010

KW-0677

Repeat

5 of 1186

0.89

0.47

0.0497

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00875

BTB And C-terminal Kelch

3 of 56

1.99

1.29

0.0031

SM00225

Broad-Complex, Tramtrack and Bric a brac

3 of 158

1.54

0.73

0.0316

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