STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R7VEQ8_CAPTEUncharacterized protein. (985 aa)    
Predicted Functional Partners:
R7TKP6_CAPTE
Uncharacterized protein.
    
 0.918
R7VCC8_CAPTE
Uncharacterized protein.
    
 0.912
R7TDP5_CAPTE
Uncharacterized protein.
   
 0.907
R7TTW2_CAPTE
NTF2 domain-containing protein.
    
 0.888
R7T5N4_CAPTE
REPA_OB_2 domain-containing protein.
   
 0.881
R7V2A0_CAPTE
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 0.881
R7UCC7_CAPTE
ERCC4 domain-containing protein.
    
 0.873
R7URX3_CAPTE
Uncharacterized protein.
    
 0.870
R7VA11_CAPTE
DUF1767 domain-containing protein.
    
 0.870
R7VCK8_CAPTE
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.852
Your Current Organism:
Capitella teleta
NCBI taxonomy Id: 283909
Other names: C. teleta, Capitella sp. I, Capitella sp. I AF-2005, Capitella sp. I ECS-2004, Capitella sp. I ES-2005, Capitella sp. MKJ-2016, Capitella teleta Blake, Grassle & Eckelbarger, 2009
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.