node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gltB | hemE | IL1075 | IL2306 | Glutamate synthase, large subunit. | Uroporphyrinogen-III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.785 |
gltB | hemL | IL1075 | IL2245 | Glutamate synthase, large subunit. | Glutamate-1-semialdehyde aminotransferase. | 0.537 |
gltB | hemN | IL1075 | IL0190 | Glutamate synthase, large subunit. | Coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.674 |
hemA | hemB | IL0926 | IL2365 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.868 |
hemA | hemC | IL0926 | IL2558 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.983 |
hemA | hemD | IL0926 | IL2559 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.515 |
hemA | hemE | IL0926 | IL2306 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen-III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.656 |
hemA | hemH | IL0926 | IL2347 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.419 |
hemA | hemL | IL0926 | IL2245 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate-1-semialdehyde aminotransferase. | 0.989 |
hemB | hemA | IL2365 | IL0926 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.868 |
hemB | hemC | IL2365 | IL2558 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.995 |
hemB | hemD | IL2365 | IL2559 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.836 |
hemB | hemE | IL2365 | IL2306 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen-III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.752 |
hemB | hemF | IL2365 | IL0023 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.428 |
hemB | hemH | IL2365 | IL2347 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.509 |
hemB | hemL | IL2365 | IL2245 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Glutamate-1-semialdehyde aminotransferase. | 0.992 |
hemC | hemA | IL2558 | IL0926 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.983 |
hemC | hemB | IL2558 | IL2365 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.995 |
hemC | hemD | IL2558 | IL2559 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.997 |
hemC | hemE | IL2558 | IL2306 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Uroporphyrinogen-III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.985 |