STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KJK39970.1ATP-dependent protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)    
Predicted Functional Partners:
KJK34687.1
Thiamine biosynthesis protein ThiF; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.901
KJK34698.1
Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...]
    
 0.901
KJK37933.1
Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.897
KJK34578.1
Peptidase M14; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.876
KJK39969.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
       0.873
KJK39971.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.871
KJK39972.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.767
KJK40154.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.749
sbcD
Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
    
 0.749
KJK37177.1
Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.749
Your Current Organism:
Streptomyces variegatus
NCBI taxonomy Id: 284040
Other names: ATCC 43696, DSM 41464, IFO 15462, INA T-511, JCM 6930, LMG 20315, LMG:20315, NBRC 15462, S. variegatus, VKM Ac-846
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.