STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rimORibosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (465 aa)    
Predicted Functional Partners:
rlmN
RNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.852
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
   0.802
KJK39725.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
  
  
 0.791
KJK39726.1
Phosphatidylglycerophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.786
KJK39728.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.751
KJK37616.1
rRNA cytosine-C5-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.730
KJK39724.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.715
KJK39757.1
Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.668
KJK39723.1
Ferritin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family.
       0.656
KJK39729.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.629
Your Current Organism:
Streptomyces variegatus
NCBI taxonomy Id: 284040
Other names: ATCC 43696, DSM 41464, IFO 15462, INA T-511, JCM 6930, LMG 20315, LMG:20315, NBRC 15462, S. variegatus, VKM Ac-846
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.