STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KJK35930.1MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)    
Predicted Functional Partners:
KJK35931.1
5-amino-6-(5-phosphoribosylamino)uracil reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.785
ribA-2
GTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
       0.764
KJK35753.1
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.581
mca
GlcNAc-PI de-N-acetylase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
     0.481
KJK37407.1
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.473
mshD
Mycothiol acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
     0.431
KJK34293.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.426
KJK41651.1
DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.425
KJK34904.1
Cytochrome B561; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.424
clpS
Clp protease ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
  
    0.423
Your Current Organism:
Streptomyces variegatus
NCBI taxonomy Id: 284040
Other names: ATCC 43696, DSM 41464, IFO 15462, INA T-511, JCM 6930, LMG 20315, LMG:20315, NBRC 15462, S. variegatus, VKM Ac-846
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.