SDW40690.1 protein (Haloarcula vallismortis)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

SDW40690.1

acyl-CoA thioester hydrolase. (147 aa)

Predicted Functional Partners:

SDW72378.1

0.676

SDW93634.1

0.625

SDW28615.1

0.615

SDX30161.1

0.615

SDW42476.1

0.589

SDW40724.1

0.586

menB

0.578

SDW33054.1

0.576

menA

0.548

SDW94288.1

0.548

Your Current Organism:

Haloarcula vallismortis

NCBI taxonomy Id: 28442
Other names: ATCC 29715, CGMCC 1.2048, DSM 3756, H. vallismortis, Halobacterium vallismortis, IFO 14741, JCM 8877, NBRC 14741, strain J. F. 54

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDW28615.1	SDW40690.1	SAMN05443574_102272	SAMN05443574_103117	Acyl-CoA hydrolase.	acyl-CoA thioester hydrolase.	0.615
SDW33054.1	SDW40690.1	SAMN05443574_102450	SAMN05443574_103117	Hypothetical protein.	acyl-CoA thioester hydrolase.	0.576
SDW40690.1	SDW28615.1	SAMN05443574_103117	SAMN05443574_102272	acyl-CoA thioester hydrolase.	Acyl-CoA hydrolase.	0.615
SDW40690.1	SDW33054.1	SAMN05443574_103117	SAMN05443574_102450	acyl-CoA thioester hydrolase.	Hypothetical protein.	0.576
SDW40690.1	SDW40724.1	SAMN05443574_103117	SAMN05443574_103118	acyl-CoA thioester hydrolase.	Hypothetical protein.	0.586
SDW40690.1	SDW42476.1	SAMN05443574_103117	SAMN05443574_103178	acyl-CoA thioester hydrolase.	NADP-dependent 3-hydroxy acid dehydrogenase YdfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.589
SDW40690.1	SDW72378.1	SAMN05443574_103117	SAMN05443574_10656	acyl-CoA thioester hydrolase.	Nitronate monooxygenase.	0.676
SDW40690.1	SDW93634.1	SAMN05443574_103117	SAMN05443574_11011	acyl-CoA thioester hydrolase.	4-hydroxybenzoate polyprenyltransferase.	0.625
SDW40690.1	SDW94288.1	SAMN05443574_103117	SAMN05443574_11040	acyl-CoA thioester hydrolase.	4-hydroxybenzoate polyprenyltransferase.	0.548
SDW40690.1	SDX30161.1	SAMN05443574_103117	SAMN05443574_12614	acyl-CoA thioester hydrolase.	Acyl-CoA hydrolase.	0.615
SDW40690.1	menA	SAMN05443574_103117	SAMN05443574_10465	acyl-CoA thioester hydrolase.	1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.	0.548
SDW40690.1	menB	SAMN05443574_103117	SAMN05443574_10470	acyl-CoA thioester hydrolase.	1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.	0.578
SDW40724.1	SDW40690.1	SAMN05443574_103118	SAMN05443574_103117	Hypothetical protein.	acyl-CoA thioester hydrolase.	0.586
SDW42476.1	SDW40690.1	SAMN05443574_103178	SAMN05443574_103117	NADP-dependent 3-hydroxy acid dehydrogenase YdfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	acyl-CoA thioester hydrolase.	0.589
SDW72378.1	SDW40690.1	SAMN05443574_10656	SAMN05443574_103117	Nitronate monooxygenase.	acyl-CoA thioester hydrolase.	0.676
SDW93634.1	SDW40690.1	SAMN05443574_11011	SAMN05443574_103117	4-hydroxybenzoate polyprenyltransferase.	acyl-CoA thioester hydrolase.	0.625
SDW93634.1	SDW94288.1	SAMN05443574_11011	SAMN05443574_11040	4-hydroxybenzoate polyprenyltransferase.	4-hydroxybenzoate polyprenyltransferase.	0.784
SDW93634.1	menA	SAMN05443574_11011	SAMN05443574_10465	4-hydroxybenzoate polyprenyltransferase.	1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.	0.586
SDW94288.1	SDW40690.1	SAMN05443574_11040	SAMN05443574_103117	4-hydroxybenzoate polyprenyltransferase.	acyl-CoA thioester hydrolase.	0.548
SDW94288.1	SDW93634.1	SAMN05443574_11040	SAMN05443574_11011	4-hydroxybenzoate polyprenyltransferase.	4-hydroxybenzoate polyprenyltransferase.	0.784

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

23

PPI enrichment p-value:

3.5e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 122

1.57

3.21

1.85e-12

GO:0044249

Cellular biosynthetic process

11 of 828

0.78

0.8

3.45e-07

GO:1901576

Organic substance biosynthetic process

11 of 847

0.77

0.78

3.92e-07

GO:0044238

Primary metabolic process

11 of 1510

0.52

0.44

0.00016

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 52

1.94

5.45

3.70e-16

GO:0019843

rRNA binding

9 of 40

2.01

5.45

5.83e-15

GO:0003723

RNA binding

10 of 92

1.69

4.0

1.82e-14

GO:0000049

tRNA binding

3 of 23

1.77

1.3

0.0021

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 59

1.88

5.24

2.16e-16

GO:0015935

Small ribosomal subunit

3 of 6

2.35

2.49

1.69e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1955

Ribosome, and Translation regulator activity

10 of 69

1.82

4.63

6.55e-15

CL:1961

Ribosome

9 of 57

1.85

4.56

8.31e-14

CL:2046

rRNA-binding, and Protein transport by the Sec complex

4 of 13

2.14

2.77

2.34e-06

CL:1968

Ribosome

3 of 13

2.02

1.77

0.00030

CL:1962

Ribosome

4 of 42

1.63

1.65

0.00015

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 56

1.91

5.4

1.16e-16

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0022627

Cytosolic small ribosomal subunit

6 of 10

2.43

5.22

2.88e-11

GOCC:0005840

Ribosome

8 of 47

1.89

4.22

6.93e-12

GOCC:0043229

Intracellular organelle

10 of 592

0.88

0.96

2.24e-07

GOCC:0005622

Intracellular

11 of 1874

0.42

0.36

0.00067

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

9 of 38

2.03

5.73

1.08e-15

KW-0689

Ribosomal protein

10 of 64

1.85

4.97

6.89e-16

KW-0820

tRNA-binding

2 of 13

1.84

0.87

0.0210

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