STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDW81018.1Replicative DNA helicase Mcm; Belongs to the MCM family. (698 aa)    
Predicted Functional Partners:
SDW66207.1
Replicative DNA polymerase I.
  
 0.957
SDX24003.1
DNA polymerase I.
  
 0.945
SDX21435.1
DNA polymerase I.
  
 0.944
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
 0.925
priL
DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
   
 
 0.925
SDX14082.1
Cell division control protein 6; Involved in regulation of DNA replication.
  
 0.907
SDX23976.1
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
  
 0.900
SDX34223.1
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
  
 0.900
SDW79839.1
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
 
 0.896
SDX36151.1
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
  
 0.895
Your Current Organism:
Haloarcula vallismortis
NCBI taxonomy Id: 28442
Other names: ATCC 29715, CGMCC 1.2048, DSM 3756, H. vallismortis, Halobacterium vallismortis, IFO 14741, JCM 8877, NBRC 14741, strain J. F. 54
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.