Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AOP32474.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (298 aa)    
Predicted Functional Partners:
AOP32472.1
Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.856
AOP33474.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.799
pheA
P-protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.794
AOP32473.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
AOP32546.1
Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.764
rpoD
RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.739
cobB
NAD-dependent deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
  
    0.726
AOP33320.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
   0.710
AOP33820.1
Flagellar biosynthesis protein FlgC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.670
AOP33950.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
   0.670
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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