Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AOP35855.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)    
Predicted Functional Partners:
AOP32861.1
Adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.771
efp
Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
 0.759
AOP32862.1
Pathogenicity locus; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.738
AOP32860.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.523
AOP32857.1
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.482
nuoH
NADH-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
   
    0.459
guaA
Glutamine-hydrolyzing GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.444
AOP35023.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.435
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
   
   0.412
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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