close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP33437.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)    
Predicted Functional Partners:
AOP35942.1
ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.840
AOP33436.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.821
pheA
P-protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.612
AOP35837.1
NAD(P)H-nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.609
A0128_05305
Endonuclease/exonuclease/phosphatase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.592
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.584
AOP33438.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.527
AOP32490.1
Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.514
AOP36094.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.451
AOP33968.1
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.449
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.