Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AOP34042.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)    
Predicted Functional Partners:
AOP34043.1
VWA containing CoxE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.965
AOP36271.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.834
AOP34040.1
Peptidase inhibitor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.700
AOP34038.1
Peptidase C69; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.620
AOP34039.1
Zn-dependent protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.620
pbpC
Penicillin-binding protein 1C; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.597
AOP32546.1
Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.547
AOP33215.1
acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.524
AOP34036.1
HIT family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.462
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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