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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP36013.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)    
Predicted Functional Partners:
AOP34078.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.672
fbp
Fructose-bisphosphatase; Catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family.
       0.659
AOP34077.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.648
rpsU
30S ribosomal protein S21; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS21 family.
       0.557
AOP34079.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.493
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
       0.473
rpoD
RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.437
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.