STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoDRNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (585 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.973
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.972
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.971
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.961
AOP35622.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.933
nusA
Transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination.
 
 
 0.868
AOP35724.1
Cysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.844
AOP32423.1
ArsC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family.
    
 
 0.827
AOP32932.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 
 0.820
AOP32474.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 
 0.814
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.