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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP34213.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)    
Predicted Functional Partners:
AOP34212.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
0.818
AOP36561.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.705
AOP33957.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.690
AOP33559.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.680
AOP34977.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.680
AOP32880.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.638
AOP35847.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.600
AOP35023.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.589
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.568
AOP35677.1
DNA gyrase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.568
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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