close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP34326.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)    
Predicted Functional Partners:
AOP34325.1
1-aminocyclopropane-1-carboxylate deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.726
lepA
Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.644
AOP32483.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.519
AOP32564.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.466
AOP35028.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.464
AOP36244.1
Transglutaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.443
AOP35985.1
Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.434
AOP33307.1
Dolichyl-phosphate-mannose--protein mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.431
AOP33654.1
Plastocyanin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.419
AOP33927.1
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.414
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.