close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP34433.1Polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (662 aa)    
Predicted Functional Partners:
AOP34434.1
RNA polymerase subunit sigma-70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
    0.849
AOP34430.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RemA family.
 
     0.840
AOP34432.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.840
AOP34436.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.778
flgB
Flagellar biosynthesis protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
     0.748
AOP34431.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.747
fliH
Flagellar assembly protein FliH; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.738
AOP34283.1
Chemotaxis protein CheX; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.719
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
     0.707
flhF
Flagellar biosynthesis protein FlhF; Positive regulator of class III flagellar genes; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.687
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
Server load: low (40%) [HD]