close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP34498.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (458 aa)    
Predicted Functional Partners:
AOP34286.1
Cytochrome oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
AOP36052.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.879
AOP34287.1
Cytochrome oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.848
AOP32855.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.847
AOP34500.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.840
coxB
Cytochrome C oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
    
 0.793
AOP34499.1
Glycosyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.788
A0128_05305
Endonuclease/exonuclease/phosphatase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.722
AOP35869.1
Glycosyl hydrolase family 5; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.634
AOP36287.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.594
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.