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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP35055.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)    
Predicted Functional Partners:
AOP35056.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.987
AOP33260.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.960
AOP33259.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.927
AOP34752.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.927
AOP35922.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.923
AOP35984.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.923
AOP35597.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.918
AOP33242.1
Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.842
AOP32934.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.819
AOP34064.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.794
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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