Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AOP35380.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (431 aa)    
Predicted Functional Partners:
AOP33260.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.820
AOP33242.1
Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.755
AOP36561.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.726
AOP32934.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.712
AOP36263.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.701
AOP33015.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.699
AOP32686.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 0.695
AOP36016.1
PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.691
AOP35893.1
Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.686
AOP33559.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.676
Your Current Organism:
Leptospira alstonii
NCBI taxonomy Id: 28452
Other names: ATCC BAA-2439, L. alstonii, Leptospira alstoni, Leptospira alstonii Smythe et al. 2013, Leptospira genomosp. 1, strain 79601
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